Carboxytherapy is an advanced, non-invasive cosmetic procedure that involves the controlled injection of carbon dioxide (CO₂) gas into the skin or subcutaneous tissue. Originally used to treat vascular diseases, this technique is now widely used to rejuvenate the skin, reduce cellulite, improve scars, and remove dark spots. According to recent studies, the mechanism of action of carboxytherapy includes increased oxygenation, stimulation of neovascularization (the formation of new blood vessels), and activation of biochemical processes related to collagen and elastin regeneration. (Kroumpouzos et al., 2021)In this article, all aspects of carboxytherapy will be reviewed, from its benefits and side effects to its various applications.
What is carboxytherapy and how does it rejuvenate the skin?
Injecting CO₂ into the skin causes several physiological changes that help improve the condition of the skin. By stimulating receptors sensitive to changes in pH and dissolved gases, this gas causes a significant increase in blood flow to the treatment area. The increased blood flow, along with the stimulation of the production of vascular endothelial growth factor (VEGF) and transforming growth factor-beta (TGF-β1), plays an important role in tissue repair, collagen fiber rearrangement, and skin elasticity. (Bagherani et al., 2024).
Also, the effect of بوهر (Bohr Effect) is one of the mechanisms is the key of this method. CO2 تزریقشده by changing the pH balance in the tissue, thereby increasing the اکسیژنرسانی to the cells of the skin. This process, especially in reducing the تیرگیهای under the eyes and skin rejuvenation damaged from sunlight are effective (Eyraud et al., 2021).
Reviews the pathological and ایمونوهیستوشیمیایی have shown that کربوکسیتراپی increases the thickness of the epidermis and the dermis, and the reorganization of collagen and elastin fibers it stimulates. In a randomized and controlled on ۱۵ ill patients with aging skin, it was determined that injection weekly CO2 to the duration ۱۰ meeting caused a dramatic increase in the thickness of the epidermis and improve the structure of collagen and elastin was (Bagherani et al., 2024).
In addition, studies have shown that کربوکسیتراپی effective role in the improvement of atrophic scars and reduce wrinkles skin there. Reviews conducted with the use of imaging ۳D of the skin have shown that this method increases the quality of the skin, reducing the graceful lines and increase hydration to the deep layer of the skin is (Stolecka-Warzecha et al., 2022).
Compare کربوکسیتراپی with other methods of skin rejuvenation
In comparison with methods such as CO2 laser treatment and radio frequency (RF) (RF), etc. کربوکسیتراپی effects منحصربهفردی stimulate the production of elastic fibers and improve the skin there. In a comparative study, etc., it became clear that radio frequency (RF) effect طولانیمدتتری on the rearrangement of the collagen are, but کربوکسیتراپی enhance elastin fibers, which is for the flexibility of the skin, importance, there is (Pinheiro et al., 2015).
On the other hand, in studies that have examined the effects of کربوکسیتراپی on rejuvenation of the skin after treatment with the fractional radio frequency (RF) trend is obvious. it is shown that the use of masks carboxy after laser therapy improves faster skin tissue and reduce side effects such as redness and inflammation is (Medrano et al., 2021).
Why کربوکسیتراپی popular?
۱. Non-invasive approach without the need for surgery: unlike the methods of cosmetic surgery such as Face Lift or fat injection, etc. کربوکسیتراپی no need for anesthesia or recovery long no.
۲. Recovering short, and the lack of need to relax: people can immediately after doing this method to work and daily activities of your return.
۳. Effects rigs: کربوکسیتراپی in the treatment of چینوچروکها, etc. Wicker dermal, cellulite, scars, steel, and even hair loss is effective (Zelenkova & Wollina, 2023).
۴. Increase the production of collagen and elastin: this method through the stimulation of فیبروبلاستها, improve the elasticity of skin and reduce the signs of aging is.
۵. High safety and minimal side effects: دیاکسید carbon is a natural gas in the body and injecting it no reaction آلرژیکی not creating.
کربوکسیتراپی as one of the methods popular in the field of rejuvenation, and medical, beauty, etc. with the use of mechanisms of the natural body, improve skin, reduce چینوچروک and increase the elasticity of it. High safety, etc. the results of the rapid and wide applications of the method to one of the best options for people who are looking for skin rejuvenation are, etc. has become. Scientific Research, New continues to examine the effects of this method are discussed and Horizons New Treatments, Beauty, and medical we have been.
- The benefits of carboxy therapy for rejuvenation and wrinkles
✅ Increase the production of collagen and elastin
- Injection of CO2 causes the activation فیبروبلاستها and the production of collagen and elastin increases, which leads to increasing the strength and flexibility of the skin is (Bagherani et al., 2024).
✅ Reduces superficial and deep wrinkles
- Stimulates the processes of tissue repair and increase اکسیژنرسانی, etc., thereby reducing the wrinkles, delicate, and improve the depth of چینوچروکهای skin is (Zelenková & Wollina, 2023).
✅ Improve elasticity of skin
- Increasing the thickness of the epidermis and the reconstruction Matrix خارجسلولی, etc. lead to increase stiffness and reduce sagging skin. This feature. کربوکسیتراپی to be one of the effective methods in the treatment of loose skin and drooping in different areas of the body has become (Medrano et al., 2021).
✅ Reduce darkness and puffiness under the eyes
- Increase blood circulation, topical and اکسیژنرسانی to the area around the eyes, etc. to reduce the accumulation of pigment melanin and improve the puff and blur under the eyes helps (Eyraud et al., 2021).
✅ Rejuvenation and increase skin transparency
- Increase moisture and hydration deep into the layers of the skin, etc. led to the creation of skin ... read more lighter and tissue صافتر is. This method is for people who suffer from fatigue, skin and staining it. it is very useful (Kroumpouzos et al., 2021).
✅ Helps to eliminate scars and scar
- Studies have shown that کربوکسیتراپی can improve atrophic scars, etc. rather than wounds caused by acne and stretch are trademarks be. This is due to the increased production of collagen and نئوواسکولاریزاسیون (creation of new blood vessels) in the area of the treatment is (Stolecka-Warzecha et al., 2022).
Applications of therapy, carboxy therapy in medical
🔹 The treatment of wounds, diabetic
🔹 Improve the Turks of the skin (striae)
🔹 Increase the speed up healing of wounds,
🔹 Arthritis treatment and joint pain
Carboxy therapy for the treatment of signs of aging, wrinkles around eyes
Scientific studies have shown that the injection CO2 To the area around the eyes Cause The dramatic increase blood circulation, topical, etc., stimulating the production of collagen and increase the اکسیژنرسانی Is. These changes
Leads to the following are:
- Reduce the accumulation of pigment melanin In the thin skin around the eyes and improve The blur caused by lack of اکسیژنرسانی (Eyraud et al., 2021).
- Increase the elasticity of the skin and stimulate the production of collagen and elastin fibers, Which reduces the wrinkles of the surface and improve the elastic skin is (Bagherani et al., 2024).
- Reduce the accumulation of fluids and lymph in the eyelids, Which reduces puffiness and improve the appearance of younger eyes is (Zelenková & Wollina, 2023).
Clinical studies have shown that after several sessions کربوکسیتراپی:
✅ Significant improvement in the amount of discoloration around the eyes And increasing the transparency of the skin is visible.
✅ Reduce wrinkles, delicate, and increasing the thickness of the skin around the eyes Occurs.
✅ Puff and inflammation of the eyelids is reduced And skin areas around the eyes صافتر And یکنواختتر is (Eyraud et al., 2021).
Steps to do a carboxy therapy: what to expect should have?
🔹 Clean the desired area
🔹 Local anesthesia (if needed)
🔹 Injection of CO2 gas with a needle very elegant
🔹 Gentle massage for better distribution of gas in the tissues
🔹 مدتزمان each session: ۱۵ up ۳۰ minutes
Possible side effects and safety tips carboxy therapy
✅ Redness, swelling, temporary
✅ Feel a slight irritation at the injection site
✅ The possibility of minor bruises in some cases
⚠ These side effects usually within a few hours to a day eases are.
Care after doing carboxy therapy
🔹 Lack of Clea the treated area to the duration ۴ up ۶ hours
🔹 Avoid from direct sun and use sunscreen
🔹 Avoid strenuous activities physical duration ۲۴ hours
Contraindication to the use of carboxy therapy
❌ Pregnant and lactating women
❌ People suffering from cardiovascular diseases
❌ Patients with skin infections active
❌ People, problems with blood clotting
Compare carboxy therapy with other methods of skin rejuvenation
In comparison with methods such as Mesotherapy and میکرونیدلینگ, etc. carboxy therapy is a noninvasive procedure with recovering shorter, and the results more natural it is.
| Method | The amount of shelf life | Recovering | The impact on چینوچروکهای deep |
| Carboxy therapy | 6 to 12 months | No | ✅ Effective |
| Mesotherapy | 3 to 6 months | Short | ❌ Less effective |
| Hypnotherapy | 1 to 2 years | No | ✅ Very effective |
| Laser rejuvenation | 6 months to 1 year | 3 to 5 days | ✅ Effective |
FAQ
❓ Carboxy therapy a few sessions require?
✔ Package to the desired area and the severity of the problem. ۶ up ۱۰ session is recommended.
❓ Results carboxy therapy, how viable is it?
✔ Lasting results between ۶ months to ۲ year is variable and depending on the life style and the type of skin a person has.
❓ Do carboxy therapy painful?
✔ Good, but may feel heat or pressure, mild at the injection site be created.
❓ How long will it take until the results of carboxy therapy view be?
✔ Some results immediately are visible, but the impact of complete, usually after a few sessions appears.
Carboxy therapy is one of the best methods of non-invasive for the skin rejuvenation, reduction چینوچروک and treatment, the darkness around the eyes. This method stimulates the blood circulation and collagen production, etc. skin شادابتر and younger to you the gift of.
💎 If you are looking for a method of non-invasive and effective for rejuvenation of your skin, you carboxy therapy is a great option for you! Today to get expert advice and do the treatments, facial rejuvenation with carboxy therapy, with an expert team doctor laden Parsa call and a giant step towards having the skin younger and شادابتر remove.
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This is more in collaboration with the production team content, specialized, and under the supervision of Dr. laden Parsa Has been prepared.
📌 Collecting and compiling: Samaneh Nikrai
